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The SAR analysis revealed that an aspartyl residue at the S 2 position was superior for inhibitory efficacy compared to succinyl and glutamyl moieties

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Coordination of innate and adaptive immunity Nanoparticles achieve synergistic regulation of innate and adaptive immunity by modulating macrophage polarization and promoting the proliferation of regulatory T cells (Treg) and type 2 innate lymphoid cells (ILC2), demonstrating potential for the treatment of RIRI

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