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Gastroenterology 138 (Suppl 1), S713 (2010)
In the multicenter SURMOUNT trial, a 72-week treatment with tirzepatide, a dual GLP-1R/GIPR agonist, resulted in a 20.9% reduction in body weight17.7% greater than that observed in the placebo group
You can have an increase in hunger when you stop taking it, which could result in weight gain
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GLP analogs bind GLP-1 receptors in the brain involved in appetite regulation
Such patients often spend excessive time on the toilet or become chronic users of cathartics
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