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IV and short-duration oral trials METAOD001-004 enrolled smaller groups of healthy or obese men with single doses or 1-week dosing across IV (25-400 mcg/kg) and oral (9-54 mg) routes

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Bacteriostatic water also can't be used for IV administration without an isotonic admixture, because plain bacteriostatic water without a solute is hypotonic and can cause hemolysis on IV push

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