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Increased intestinal permeability is facilitated by a high-fat diet (HFD) 22 , and may allow for bacterial translocation from the gut to adipose tissue 23
Methylcobalamin is distributed into breast milk in amounts similar to those in maternal plasma, and distribution in breast milk allows for adequate intakes of methylcobalamin by breastfeeding infants
For maintenance or prophylactic use (such as in a patient with short-gut syndrome who cannot absorb oral vitamins well), a common regimen is 1 mL IM once weekly
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PMC 5110436
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