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Cotadutida es un coagonista GLP-1/GCG equilibrado derivado de oxintomodulina de administracin diaria que ha demostrado un moderado efecto reductor de peso en pacientes con diabetes y obesidad, con capacidad de disminuir la fraccin heptica de grasa evaluada mediante densidad protnica por resonancia magntica, as como marcadores de dao heptico y fibrosis51