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Healthcare experts have raised concerns about: contamination or impurities inconsistent potency incorrect dosing use of unapproved semaglutide salt forms Some reports and studies have suggested that compounded GLP-1 products may be associated with higher rates of adverse events and product-quality concerns compared with FDA-approved medications
International Journal of Food Microbiology, 191, 19
A phase 3 clinical trial involved 1,879 participants to compare the effectiveness of semaglutide and tirzepatide over 40 weeks
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Despite the attenuated weight loss outcomes, one finding that surprised the research team was that patients who discontinued therapy did not experience the rapid weight regain often seen in trial settings
