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Another clinical trial utilized NR to help ameliorate heart failure (HF), which is also characterized by a decline in NAD + levels in whole blood 317,318

Learning from others saves you weeks of trial and error

Hylander BL, Qiao G, Cortes Gomez E, Singh P, Repasky EA

Vitamin B12 Deficiency in Dogs Without enough vitamin B12, many of a dogs enzymatic and metabolic processes cant proceed normally, which results in clinical signs like: Poor growth in young animals Anemia (low red blood cell counts) Neurologic dysfunction Importantly, these signs are also often seen with the very health problems that lead to vitamin B12 deficiency

After 14 years of research and testing, we finally had proof of concept

In clinical trials, the drugs have led to patients losing up to 18 percent of their bodyweight compared to a placebo (1)