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A consultation is required to determine whether treatment is safe and appropriate

The fact that NRF2 is readily inducible in cultured astrocytes suggests that most pharmacological NRF2 activators may specifically target astrocytes in vivo, although there is still limited direct evidence for this

Vitamin B12

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Disulfide bonds within these cleavable linkers remain stable in the relatively oxidizing conditions of the bloodstream but are cleaved in the reducing environment of the cytoplasm, thereby releasing the cytotoxic drug specifically within cancer cells