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Rybelsus: The oral version of Semaglutide for managing type 2 diabetes

While these promising results in the rat model cannot be directly extrapolated to humans, they nonetheless lay a scientific foundation for future translational research and clinical trials to explore combinatorial strategies addressing both metabolic and neurodegenerative complications of diabetes

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2 Global knockout of Gs signaling in Glp1r-expressing cells abolishes brain-wide semaglutide-induced Fos activation

The gradual dose escalation minimizes gastrointestinal adverse effects, which represent the most common side effects of the medication