Obesity in men is associated with lower testosterone and sperm issues, so losing even 5-10% of body weight if overweight can improve hormone balance and sperm parameters
Q4W=once every 4 weeks
reassessment should occur after 812 weeks with clinical guidance
doi: 10.3389/fbioe.2025.1729166 Received 21 October 2025 Revised 01 December 2025 Accepted 17 December 2025 Published 15 January 2026 Volume 13 - 2025 Edited by Ling Wang, Dalian Medical University, China Reviewed by Nicola Alessio, University of Campania Luigi Vanvitelli, Italy Yesuf Adem Siraj, Bahir Dar University, Ethiopia Updates Copyright 2026 Hu, Li, Hu, Shan, Tang, Jiang, Yi, Chen, Jin, Wang and Wang
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The animals were provided with standard food and water ad libitum