Liraglutide suppresses obesity and induces brown fat-like phenotype via soluble guanylyl cyclase mediated pathway in vivo andin vitro
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[15] Methionine donates methyl groups for the synthesis of S-adenosyl-methionine, which in turn drives phosphatidylcholine production and very-low-density lipoprotein assembly, facilitating export of triglycerides from hepatocytes and mitigating diet-induced steatosis
In an AD mouse model, liraglutide reduces the activation of the NLR family pyrin domain containing 3 (NLRP3) inflammasome in the microglia, leading to the decreased production of proinflammatory cytokines and A plaques [52]
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