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Saudi J Gastroenterol (2013) 19:131
JSTOR 3870806
Additionally, if youre experiencing any of the following symptoms alongside constipation, see a doctor as soon as possible ( bleeding from the rectum constant abdominal pain blood in your stool inability to pass gas lower back pain vomiting fever unexplained weight loss You may feel uncomfortable talking about constipation with your doctor, but its important to keep them informed of any health changes, including changes in your bowel movements, so they can provide you with appropriate care
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In the present post hoc analysis published in Diabetes Care , Klein and colleagues examined data on the 16 996 adults participating in four large randomised, double-blind, placebo-controlled clinical trials assessing the safety and efficacy of GLP-1 RAs: the LEADER trial of liraglutide, the STEP 2 and SUSTAIN 6 trials of subcutaneous semaglutide, and the PIONEER 6 trial of oral semaglutide
