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In both cases, modifications made to the structures of the peptides cause their bioavailability to be increased dramatically compared to the hormones secreted naturally by the intestine, from just a few minutes to more than a hundred hours, which allows these drugs to be administered by subcutaneous injection only once a week

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To date, no approved treatment has been shown to directly improve renal function in chronic HF patients

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The article is based on the results of animal experiments