Patients with UC produce large amounts of ROS and experience genetic material damage [80, 245], particularly in the rectum or sigmoid colon
Albeit the FDA included the black box warning, but multiple studies, independent and meta analysis have come out that show zero increased risk for thyroid cancer of any kind associated with GLP1s
Gastrointestinal issues such as nausea, vomiting, constipation and diarrhoea are common, with more serious complications including gallbladder inflammation and pancreatitis reported in a minority of patients
doi: 10.1016/j.peptides.2019.170183 47 HolstJJRosenkildeMM
These studies were limited by the small number of patients and limited follow-up duration
Best Probiotics for GLP-1 Bloating and Gut Discomfort What Are the Best Probiotics for GLP-1 Bloating and Gut Discomfort