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The evaluation included both nerve conduction studies and patient-reported changes in CIPN symptoms

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The average initial homocysteine was 8.5 umol/L

Despite wide dose ranges tested (6 g/kg to 20 mg/kg), multiple administration routes (intramuscular, intraperitoneal, intravenous, oral), and varied dosing frequencies across numerous animal models, no acute lethal dose has been identified

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History The development of Cagrilintide emerged from ongoing research into hormones that help regulate food intake and energy metabolism