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Nf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferase

J Clin Endocrinol Metab 103:41044112 Paccou J, Martignne N, Lespessailles E et al (2020) Gastric Bypass But Not Sleeve Gastrectomy Increases Risk of Major Osteoporotic Fracture: French Population-Based Cohort Study

Practically, this means setting different goals, allowing more time to increase the dose, and using monitoring methods that focus on early symptom signs and how well people stick to the treatment, rather than only looking at blood sugar numbers

4 and 5, Extended Data Fig

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Being overweight or obese places you at risk for a wide range of health conditions including heart disease, diabetes, stroke, sleep apnea, and mental health conditions like depression and anxiety [2]