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for developing a novel murine closed-skull traumatic brain injury (TBI) model and using it to demonstrate that the mouse skull, whether thinned or intact, is permeable to drugs, allowing "transcranial" drug delivery into the underlying cerebral cortex with consequent reduction in injury-related cell death when glutathione is delivered

However, the extent of this effect can vary among individuals

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Furthermore, Novo Nordisk will have strengthened their market position by patenting the same drug (semaglutide) for different uses, e.g., semaglutide for use in the treatment of diabetes and separately for use in the treatment of weight loss (termed second medical use in Europe)