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Landmark cardiovascular outcome trials like LEADER and SELECT have demonstrated the cardiometabolic benefits of GLP1-RA in the reduction of MACE events in populations with T2DM as well as populations with overweight or obesity in the absence of T2DM

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For a deeper discussion of the study design and findings, see our full GLP-1 receptor agonist feasibility study on linear vs fragment SPPS

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Sun, X., Jiao, X., Ma, Y., Liu, Y., Zhang, L., He, Y., & Chen, Y

For the GSSG assay, GSH was masked by adding 20 L of 2-vinylpyridine to the neutralized supernatant, whereas 20 L of water was added for the total GSH assay