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For example, there are at least 20% of European ancestry people with type 2 diabetes who are prescribed metformin but have no response to the drug because they have a variation of the organic cation transporter 1 (OCT1), the gene that basically is responsible for metformins action
Theres no contraindication
Another potential factor is insulin resistance
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Additionally, societal pressures related to body image and weight management disproportionately affect women [25], which could further drive interest in GLP-1 and GLP-1/GIP medications within this group
Resistance training, protein, and functional monitoring do all three
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