Figures are the treatment-regimen estimand at week 72
Thermal stability: The lyophilized form is stable up to 40C for short transport excursions
In that Phase 2 trial, gastrointestinal adverse events were among the most commonly reported side effects, particularly at higher doses
Dr Simon Cork, a senior lecturer in physiology at Anglia Ruskin University, said that, despite Nice having set a threshold BMI of 35 for receipt of Mounjaro, meaning that very few patients will be given it, other people will try to get it as they have done with Wegovy
Figure 1: Changes in percentage of weight lost across all experimental treatment groups
Whilst the heart rate increases observed were statistically significant, they were not associated with a higher rate of serious adverse cardiac events in the Phase 2 data