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Beta carotene protects H9c2 cardiomyocytes from advanced glycation end product-induced endoplasmic reticulum stress, apoptosis, and autophagy via the PI3K/Akt/mTOR signaling pathway
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In the present study, the serum or gastric pro-inflammatory cytokines TNF- and IL-1 as well as the mRNA expression of NF-B were reduced by NPW treatment in the rat gastric tissue, indicating the anti-inflammatory action of NPW against acetic acid-induced gastric injury also occurs through the suppression of NF-B pathway
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doi: 10.1371/journal.pgen.1008629 50
An essential element of the NLRP1 inflammasome that activates IL-1 is the protein pyrin domain-containing protein 1 [57, 58]
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