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Meanwhile, that will promote the production of excessive reactive oxygen species (ROS), change the balance of oxidation and reduction in cells and will lead to oxidative stress (Rider et al., 2009

Others may be better served by an already approved alternative

Given that colonic mucosal damage typically initiates at the crypt surface and progresses to the base in response to harmful factors, PYY-positive cells in the superficial layer may be more susceptible to loss compared to GLP-1-positive cells in the basal layer

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To focus on the pelvic floor, tightening the pelvic floor muscles

Although not applicable for GLP-1, fusion to the C-terminal end of albumin could be an attractive approach to avoid cleavage by CPA