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When GPx levels are low, the body cannot effectively neutralize hydrogen peroxide and other reactive oxygen species
, Akuyam, S.A
Selenoprotein P and apolipoprotein E receptor-2 interact at the blood-brain barrier and also within the brain to maintain an essential selenium pool that protects against neurodegeneration
It will also be interesting to know how these regulators affect the functional coordination between GPx1 and other selenoproteins or antioxidant enzymes in various metabolic circumstances [34]
Funding This study is supported by National Research Foundation of Korea (NRF) grants funded by the Korean government (MSIT) (RS-2025-00517133)
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