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The inhibitory effect of GLP-1 on glucagon secretion in vivo is only observed at glucose levels at or above fasting levels (see Fig
Effect of weekly subcutaneous semaglutide vs daily liraglutide on body weight in adults with overweight or obesity without diabetes: The STEP 4 randomized clinical trial
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Participants also lost significantly more weight on semaglutide than placebo
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Regulatory approvals filing in future Novo Nordisk expects to file for regulatory approvals in the US and EU in the first half of 2025
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