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Strategies to Prevent Rapid Weight Regain Without Continuous Therapy If discontinuing semaglutide is necessary, evidence suggests that gradual dose reductionrather than abrupt cessationmay reduce rebound appetite severity and allow behavioral adaptations to solidify

You need a carefully planned, nutrient-dense diet rather than eating normally, as Wegovy significantly reduces appetite and food intake

Brand-name Ozempic (injectable pen) Unopened and refrigerated: 24 months from manufacture date

The minimum-acceptance threshold is 99 percent purity by HPLC

Effect of Additional Oral Semaglutide vs Sitagliptin on Glycated Hemoglobin in Adults With Type 2 Diabetes (PIONEER 3) Pieber TR, Bode B, Mertens A, et al