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In addition, the PER was also significantly increased in the shGSTM3 group than in the shNC group for PANC-1 cells

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The urine albumin-to-creatinine ratio was also markedly increased in the placebo group, with a mild increase in the probiotic-treated group

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After an additional 4 days ( t = 96 h), cells were collected by trypsinization, pelleted, snap-frozen and stored at 80 C