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Kornblau SM, Womble M, Qiu YH, Jackson CE, Chen W, Konopleva M, Estey EH, Andreeff M

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In preclinical models, it is studied to assess its influence on cellular signaling pathways involved in: Tissue remodeling Angiogenesis, and Nitric oxide modulation On the other hand, TB-500 is a synthetic analog of Thymosin Beta-4

These findings suggest that monocyte infiltration, an established EAE severity driver 6,7 , is associated with substantial alterations of the CNS metabolic landscape linked to neurotoxicity, perturbations in energy metabolism and redox homeostasis