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In Noebels JL, Avoli M, Rogawski MA, et al

Creates irreversible structural damage that neither visual inspection nor home testing can detect

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However, given the associated risks of cardiovascular disease and various cancers, the benefits of these medications, such as better glycemic control, weight loss and improvement in cardiometabolic risk factors as well as other obesity complications, appear to outweigh the risks for most adults with obesity [143, 153]

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The discoloration follows a predictable progression from purple-red to green to yellow as the extravasated blood is metabolized and cleared