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Current therapeutic approaches, such as disease-modifying anti-rheumatic drugs (DMARDs) and biologics, are limited by infection risks, poor tissue specificity, and suboptimal long-term efficacy, underscoring the need for novel therapies

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A recent meta-analysis indicated a mean weight loss of 4.7 kg with liraglutide over a period of 3 to 6 months, corresponding to a reduction in BMI of 1.5 BMI points [22]

Researchers continue to study how combined receptor activation affects neuroendocrine circuits involved in feeding behavior and satiety signaling