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Nevertheless, degrading the ECM presents a double-edged sword: if the localized tumor destruction is incomplete, the loosened matrix could paradoxically facilitate the escape of surviving malignant cells

Mice treated with metformin showed the similar results to those from OA group in the rotarod test (Fig

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Metallothionein prevents diabetes-induced cardiac pathological changes, likely via the inhibition of succinyl-CoA:3-ketoacid coenzyme A transferase-1 nitration at Trp(374)

Importantly, the level of evidence supporting antioxidant-based interventions varies substantially across compounds

When this sphincter weakens or relaxes inappropriately, acid reflux happens