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Weight Loss Injections and Medications Comparison Medication Zepbound (GLP-1 Tirzepatide) (GLP-1 Tirzepatide) Wegovy (GLP-1 Semaglutide) (GLP-1 Semaglutide) Saxenda (Liraglutide) (Liraglutide) Wegovy Pill (GLP-1 Semaglutide) (GLP-1 Semaglutide) Foundayo (orforglipron) (orforglipron) Qsymia (Phentermine & Topiramate) (Phentermine & Topiramate) What to Expect Zepbound Once weekly injection Wegovy Once weekly injection Saxenda Once daily injection Wegovy Pill One tablet daily Foundayo One tablet daily Qsymia One tablet daily Weight loss Zepbound 16-20% of body weight Wegovy 15-18% of body weight Saxenda 15-18% of body weight Wegovy Pill 14-17% of body weight Foundayo 11-12.4% of body weight Qsymia 10% of body weight How you lose weight Zepbound Reduce appetite, food intake, body fat and body weight Wegovy Increase satiety and control portions Saxenda Increase satiety and control portions Wegovy Pill Increase satiety and control portions Foundayo Slows digestion and reduces appetite Qsymia Suppress appetite and control cravings See Your GLP-1 Weight Loss Potential Find Out How Much Weight You Could Lose with GLP-1 Injections and Oral Medications Prescription weight loss medications and injections such as GLP-1s Wegovy and Zepbound support weight loss by decreasing hunger while simultaneously increasing feelings of satiety, leading to reduced food intake and overall absorption of calories