A new study from UCLA shows metformin reduces brain inflammation in female mice with MS by targeting the X-linked gene Kdm6a, which escapes inactivation in XX chromosomes
While GLP-1 agonists work well for controlling blood sugar and helping with weight loss, its important to remember that they arent suitable for everyone, including pregnant individuals or those with certain pre-existing health conditions, like a history of pancreatitis
Many patients experience their greatest weight loss during weeks 6-12, even as nausea fades
Gastroenteritis was the most common GI side effect, with 21 and 19.1 cases per 1,000 person-years at risk for tirzepatide and semaglutide, respectively
Short-term exposure to higher humidity levels may not significantly affect the medication's stability
Most patients report noticing decreased appetite within the first 24-72 hours of their initial dose, though this subjective experience varies based on individual receptor sensitivity and baseline metabolic state