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Prohaska JR (1980)
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Some studies have suggested that the proliferation and apoptosis of granulosa cells (GCs) are the root causes of follicular development and atresia, with forkhead box protein O1 (FoxO1) playing an important role in promoting PCOS follicular atresia and GCs apoptosis (162, 163)
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165 The long-term extension of the RHAPSODY study further demonstrated that the continued use of rilonacept reduced the risk of recurrence without increasing adverse effects
